CLINICAL-EVALUATION OF S-ADENOSYL-L-METHIONINE VERSUS TRANSCUTANEOUS ELECTRICAL NERVE-STIMULATION IN PRIMARY FIBROMYALGIA
CLINICAL-EVALUATION OF S-ADENOSYL-L-METHIONINE VERSUS TRANSCUTANEOUS ELECTRICAL NERVE-STIMULATION IN PRIMARY FIBROMYALGIA
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DOI：
10.1016/s0011-393x(05)80250-4
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发表时间：
1993-02-01
影响因子：
1.9
通讯作者：
ZIDARICH, V
中科院分区：
文献类型：
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作者：
DIBENEDETTO, P;IONA, LG;ZIDARICH, V
对30例原发性纤维肌痛患者进行为期6周的对照试验，评价s -腺苷- l-蛋氨酸（SAMe）和经皮神经电刺激（TENS）的效果。与TENS不同，SAMe显著减少了压痛点的总数，对疼痛和疲劳的主观症状有显著的有益作用，并显著降低了汉密尔顿抑郁焦虑评定量表和Zung抑郁自评量表的得分。在治疗结束时，TENS组患者仅在汉密尔顿焦虑量表上表现出显著降低的得分。
The effects of S-adenosyl-L-methionine (SAMe) and transcutaneous electrical nerve stimulation (TENS) were evaluated in a 6-week controlled trial of 30 patients with primary fibromyalgia. Unlike TENS, SAMe significantly decreased the total number of tender points, had a significant beneficial effect on the subjective symptoms of pain and fatigue, and significantly reduced the scores on the Hamilton Depression and Anxiety Rating Scales and Zung's Self-Rating Scale for Depression. At the end of treatment, patients in the TENS group exhibited significantly reduced scores on the Hamilton Anxiety Scale only.