BLISS 2.0: a web-based tool for predicting conserved regulatory modules in distantly-related orthologous sequences.

BLISS 2.0: a web-based tool for predicting conserved regulatory modules in distantly-related orthologous sequences.
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BLISS 2.0:一种基于网络的工具,用于预测远缘相关的直系同源序列中的保守调控模块。

DOI:
10.1093/bioinformatics/btm368
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发表时间:
2007
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
通讯作者:
Zhou,Lei
Zhou,Lei
中科院分区:
--
文献类型:
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作者:
Meng,Hailong;Banerjee,Arunava;Zhou,Lei

文献摘要

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Summary:BLISS 2.0 is a web-based application for identifying conserved regulatory modules in distantly related orthologous sequences. Unlike existing approaches, it performs the cross-genome comparison at the binding site level. Experimental results on simulated and real world data indicate that BLISS 2.0 can identify conserved regulatory modules from sequences with little overall similarity at the DNA sequence level.Availability:http://www.blisstool.org/Contact:leizhou@ufl.edu