Comparative Anticonvulsive Action of 3,5,5-trimethyloxazolidine-2,4-dione (Tridione), Dilantin and Phenobarbital
Comparative Anticonvulsive Action of 3,5,5-trimethyloxazolidine-2,4-dione (Tridione), Dilantin and Phenobarbital
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3,5,5-三甲基恶唑烷-2,4-二酮（Tridione）、Dilantin 和苯巴比妥的抗惊厥作用比较
DOI：
10.1097/00000542-194507000-00047
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发表时间：
1944
期刊：
影响因子：
8.8
通讯作者：
R. K. Richards
中科院分区：
文献类型：
--
作者：
G. Everett;R. K. Richards
1. 3，5，5-三甲基恶唑烷-2，4-二酮（三酮）对药物和电击引起的惊厥有明显的拮抗作用，已在实验动物中得到证实。2.与苯巴比妥和苯妥英钠的比较实验表明，三酮的作用与苯巴比妥更相似，但在有效剂量下产生的抑郁症较少。
1. The marked antagonistic action of 3,5,5-trimethyloxazolidine-2,4-dione (Tridione) against convulsions produced by drugs and electrical shock has been demonstrated in experimental animals. 2. Comparative experiments with phenobarbital and dilantin revealed that tridione is more comparable to phenobarbital in its action but produces less depression in effective doses.