Brief cognitive screening of the elderly: A comparison of the mini-mental state examination (MMSE), abbreviated mental test (AMT) and mental status questionnaire (MSQ)

Brief cognitive screening of the elderly: A comparison of the mini-mental state examination (MMSE), abbreviated mental test (AMT) and mental status questionnaire (MSQ)
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DOI:
10.1017/s0033291700034826
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发表时间:
1996-03-01
影响因子:
6.9
通讯作者:
Goodwin, GM
Goodwin, GM
中科院分区:
医学1区
文献类型:
--
作者:
MacKenzie, DM;Copp, P;Goodwin, GM

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采用简易精神状态测验(MMSE)、简易精神测验(AMT)和精神状态问卷(MSQ)对150名未入选的社区老年人进行评估。评估潜在混杂(非认知)变量对认知测试分数的影响。敏感性和特异性分别为:MMSE为80%和98%;AMT分别为77%和90%;MSQ分别为70%和89%。MMSE识别的假阳性明显少于AMT和MSQ。智力对认知测试成绩的主要影响以前被低估了。年龄、社会阶层、听力敏感度和中风史也与认知测试成绩显著相关。全日制教育年限和抑郁只影响较长的MMSE和CAMCOG。MMSE(截止时间为20/21)可推荐用于常规筛查。然而,由于分数受认知功能以外的变量影响,特别是智力,对已确定病例的进一步评估可能无法揭示显著的功能损伤。
One hundred and fifty unselected elderly community subjects were assessed by Mini-Mental State Examination (MMSE), Abbreviated Mental Test (AMT) and Mental Status Questionnaire (MSQ). The effects on cognitive test scores of potential confounding (non-cognitive) variables were evaluated. Sensitivities and specificities were: MMSE 80 % and 98 %; AMT 77 % and 90 %; and MSQ 70 % and 89 %. The MMSE identified significantly fewer false positives than the AMT and MSQ. The major effect of intelligence on cognitive test scores has previously been underestimated. Age, social class, sensitivity of hearing and history of stroke were also significantly correlated with cognitive test scores. Years of full time education and depression only affected the longer MMSE and CAMCOG. The MMSE (cut-off 20/21) can be recommended for routine screening. However, as scores are affected by variables other than cognitive function, particularly intelligence, further assessment of identified cases may fail to reveal significant functional impairment.