Persistence of pain and cognitive impairment in older adults.
Persistence of pain and cognitive impairment in older adults.
复制标题
老年人持续疼痛和认知障碍。
DOI：
10.1111/jgs.17542
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发表时间：
2022-03
影响因子：
6.3
通讯作者：
Kremen WS
中科院分区：
文献类型：
--
作者：
Bell T;Franz CE;Kremen WS
没有研究检查疼痛的持续性与老年人认知问题之间的纵向关联。本研究的目的是探讨疼痛的持续性与认知能力、认知障碍和主观记忆下降的关系。在10个两年一次的波中，健康和退休研究评估了8,515名65岁及以上的成年人（法师= 74.17，SD = 6.87，59.2%为女性）。在每一波中，个体被要求报告疼痛的存在，如果存在，则评估其强度和对日常活动（如家务或家务）的干扰。使用运行频率或平均值，我们使用这三种疼痛测量方法计算疼痛的持续性。使用认知表现和不同的认知损害截止值评估认知。事件主观记忆下降额外测量为过去2年中新的自我报告的记忆变化。一般估计方程检查疼痛持续性和认知变量之间的并发关联，调整人口统计学，抑郁症状和医学合并症。疼痛的持续存在与认知障碍的风险增加有关。只有疼痛干扰的持续性，而不是疼痛强度，与认知能力较差或被归类为认知受损显著相关。每2年，疼痛干扰的持续性与认知障碍的几率增加21%相关。三个疼痛变量中只有一个与主观记忆下降有关。疼痛的持续性与社区居住的老年人的认知能力较差有关，特别是在家务和工作中受到持续干扰时。促进疼痛管理可能对帮助维持晚年认知和降低痴呆风险很重要。
No studies have examined the longitudinal association between the persistence of pain and its relationship to cognitive problems in older adults. The objective of this study was to examine how the persistent of pain associates with cognitive performance, cognitive impairment, and subjective memory decline. Across 10 biennial waves, 8,515 adults ages 65 and over were assessed from the Health and Retirement Study (Mage = 74.17, SD = 6.87, 59.2% female). At each wave, individuals were asked to report on pain presence, and if present, rate its intensity and interference with daily activities such as housework or chores. Using running frequencies or averages, we calculated the persistence of pain using these three pain measures. Cognition was assessed using cognitive performance and different cognitive impairment cutoffs. Incident subjective memory decline was additionally measured as new self-reported memory change in the last 2 years. General estimating equations examined concurrent associations between persistence of pain and cognitive variables, adjusting for demographics, depressive symptoms, and medical comorbidities. Persistence of pain presence was associated with an increased risk of cognitive impairment. Only persistence of pain interference, not pain intensity, was significantly associated with poorer cognitive performance or being classified as cognitively impaired. For every 2 years, persistence of pain interference was associated with 21% increased odds of cognitive impairment. Only one of three pain variables were related to incident subjective memory decline. Persistence of pain is associated with poorer cognitive performance in community-dwelling older adults, especially when involving ongoing interference in chores and work. Facilitating pain management might be important for helping to maintain later-life cognition and reduce dementia risk.
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影响因子：
5.3
作者：
Kuchinad, Anil;Schweinhardt, Petra;Bushnell, M. Catherine
通讯作者：
Bushnell, M. Catherine
影响因子：
4.7
作者：
Bergh, I;Steen, G;Steen, B
通讯作者：
Steen, B
DOI：
10.3390/ijerph17155454
发表时间：
2020-08-01
影响因子：
--
作者：
Khalid, Sumaira;Sambamoorthi, Usha;Innes, Kim E.
通讯作者：
Innes, Kim E.
影响因子：
5.3
作者：
Apkarian, AV;Sosa, Y;Gitelman, DR
通讯作者：
Gitelman, DR
影响因子：
7
作者：
Hill, Nikki L.;Mogle, Jacqueline;Sliwinski, Martin J.
通讯作者：
Sliwinski, Martin J.