Sex-specific trends in validated coronary heart disease rates in southeastern New England, 1980-1991.
Sex-specific trends in validated coronary heart disease rates in southeastern New England, 1980-1991.
复制标题
1980-1991 年新英格兰东南部经过验证的冠心病发病率的性别趋势。
DOI：
10.1093/oxfordjournals.aje.a010222
复制
发表时间：
2000
影响因子：
5
通讯作者：
Carleton,RA
中科院分区：
文献类型：
--
作者：
Derby,CA;Lapane,KL;Feldman,HA;Carleton,RA
尽管全国冠心病死亡率的下降开始得更早，而且女性的下降幅度比男性更大，但最近的数据表明，女性的下降速度已经放缓。这项研究的目的是记录1980-1991年期间新英格兰东南部两个社区冠心病发病率和死亡率的性别趋势，并确定35-74岁的男性和女性的时间趋势是否相似。分析基于由Pawtucket心脏健康计划的回顾监测系统确定的6282例经验证的院内和院外冠状动脉疾病事件。在此期间，总(致命性和非致命性)冠心病率保持稳定。这一趋势持平是非致命性住院人数增加以及院内和院外死亡率同时下降的结果。对于男性来说，致命冠心病的下降幅度更大，院内和院外死亡率都是如此，尽管性别差异仅在院外死亡方面具有统计学意义。男性和女性因确诊的冠心病住院病死率均有所下降。男性冠心病死亡率的急剧下降表明，在预防、诊断、分类和治疗方面需要更多关于性别差异趋势的信息。
Although the national decline in coronary heart disease mortality began earlier and was steeper in women relative to men, recent data suggest that the decline in women has slowed. The purpose of this study was to document sex-specific trends in coronary disease morbidity and mortality for the period 1980–1991 in two southeastern New England communities, and to determine whether temporal trends have been similar in men and women aged 35–74 years. Analyses were based on 6,282 validated in-hospital and out-of-hospital coronary disease events ascertained by the retrospective surveillance system of the Pawtucket Heart Health Program. Total (fatal plus non-fatal) coronary disease rates remained stable during this period. The flat trend was the result of an increase in non-fatal hospitalizations and a simultaneous decrease in both in-hospital and out-of-hospital mortality. The decline in fatal coronary disease was steeper for men, for both in-and out-of-hospital mortality, although the sex difference was statistically significant only for out-of-hospital deaths. In-hospital case-fatality for validated coronary disease declined for both men and women. The steeper decline in coronary disease mortality for men suggests the need for more information regarding sex differential trends in prevention, diagnosis, classification, and treatment.Am J Epidemiol2000;151;417–29.