Conformation and absolute configuration of (1S,2S)-2-(phenyl-selan-yl)cyclo-hexyl (R)-2-meth-oxy-2-(1-naphth-yl)propionate.
Conformation and absolute configuration of (1S,2S)-2-(phenyl-selan-yl)cyclo-hexyl (R)-2-meth-oxy-2-(1-naphth-yl)propionate.
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（1s，2s）-2-（苯基 - 硅基）环己基（R）-2-METH-METH-OXY-2-（1-萘基）丙酸的构象和绝对构型。
DOI：
10.1107/s1600536810022233
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发表时间：
2010-06-16
期刊：
影响因子：
--
通讯作者：
Kijima T
中科院分区：
文献类型：
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作者：
Murakami S;Kato A;Katagiri H;Matsumoto T;Kijima T
以（R）-（-）-2-甲氧基-2-（1-萘基）丙酸为起始原料，通过考察Bijvoet（Friedel）对，利用低温下Mo Kα辐射收集的反常色散数据，确定了标题化合物C26 H28 O3 Se的相对和绝对构型。羰基周围的几何形状存在于顺式构象中，反映在涉及这个组的扭转角，并且结构的稳定性受到弱分叉的内氢键的影响。
The relative and absolute configurations of the title compound, C26H28O3Se, were assigned from the known configuration of (R)-(−)-2-methoxy-2-(1-naphthyl)propionic acid used as starting material, and by examination of the Bijvoet (Friedel) pairs, using the anomalous dispersion data collected with Mo Kα radiation at low temperature. The geometry around the carbonyl group exists in the syn conformation, as reflected in torsion angles involving this group, and the stability of the structure is affected by weak bifurcated intramolecular C—H⋯O hydrogen bonds.