Life expectancy of HIV-positive adults: a review
Life expectancy of HIV-positive adults: a review
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DOI：
10.1071/sh11046
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发表时间：
2011-01-01
期刊：
影响因子：
1.6
通讯作者：
Ingle, Suzanne M.
中科院分区：
文献类型：
--
作者：
May, Margaret T.;Ingle, Suzanne M.
我们回顾了估计预期寿命（LE）的研究，一个人可以预期再活的平均年数，对于HIV阳性的成年人，并显示社会人口因素和免疫抑制水平的变化。在HIV感染早期开始抗逆转录病毒治疗并恢复正常CD4计数的患者的LE可能接近一般人群。治疗的改善和相关的LE增加意味着越来越多的艾滋病毒阳性患者将活到老年。晚期诊断和表现为护理和治疗不符合指南有助于减少LE。
We review studies estimating life expectancy (LE), the average number of additional years a person can expect to live, for HIV-positive adults and show variation by sociodemographic factors and level of immunosuppression. The LE of patients starting antiretroviral therapy early in the course of HIV infection and attaining restoration of a normal CD4 count may approach that of the general population. Improvements in treatment and the associated increase in LE imply that increasing numbers of HIV-positive patients will live to older age. Late diagnosis and presentation to care and treatment not concordant with guidelines contribute to reducing LE.