Age group differences in response to treatment for problematic alcohol use.
Age group differences in response to treatment for problematic alcohol use.
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年龄组对酗酒问题治疗的反应存在差异。
DOI：
10.1111/j.1360-0443.1993.tb02023.x
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
Noel,N
中科院分区：
文献类型：
--
作者：
Rice,C;Longabaugh,R;Beattie,M;Noel,N
结构特征作为改变治疗结果的标志是酒精治疗领域长期存在的想法。为了测试患者年龄是否是制定治疗分配时需要考虑的因素，我们检查了临床试验中收集的数据。 229 名患者被随机分配接受三种治疗条件之一：扩展认知行为治疗 (CB)、关系增强 (RE) 或关系和职业增强 (VE)。本文报告了治疗分配后 3-6 个月的结果（饮酒）。我们的问题是，分配给治疗条件的不同年龄组会表现出不同的结果吗？治疗条件或年龄组没有显着的主效应。年龄组相互作用存在显着的治疗状况。随着年龄的增长，治疗的差异似乎越来越大。对于较年轻的年龄组（18-29 岁），没有检测到统计学上显着的治疗差异。中年患者（30-49岁）在RE条件下表现最好。老年患者（50 岁以上）在分配到 CB 条件时表现最好。这些发现使我们得出结论，患者年龄是测试患者治疗匹配假设时应考虑的一个变量。
That structural characteristics act as markers of modified treatment outcome is a long standing idea in the alcohol treatment field. In order to test whether patient age is a factor to be considered in making treatment assignments, we examined data collected under a clinical trial. Two hundred and twenty‐nine patients were randomly assigned to one of three treatment conditions: extended cognitive behavioral treatment (CB), relationship enhancement (RE), or relationship and vocational enhancement (VE). This paper reports on outcome (alcohol use) 3‐6 months after treatment assignment. Our question was, would different age groups assigned to the treatment conditions exhibit different outcomes? There were no significant main effects by either treatment condition or age group. There was a significant treatment condition by age group interaction. With increasing age, the differences in treatment seemed to increase. For the younger aged group (18‐29 years old) no statistically significant treatment differences were detected. Middle aged patients (30‐49 years old) did best in the RE condition. Older aged patients (50 + years old) did best when assigned to the CB condition. These findings lead us to conclude that patient age is a variable which should be considered when testing patient‐treatment matching hypotheses.