Prevalence of Malnutrition Diagnosed with GLIM Criteria and Association with Activities of Daily Living in Patients with Acute Stroke
Prevalence of Malnutrition Diagnosed with GLIM Criteria and Association with Activities of Daily Living in Patients with Acute Stroke
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DOI：
10.1016/j.jstrokecerebrovasdis.2021.105989
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发表时间：
2021-07-13
影响因子：
2.5
通讯作者：
Shimada, Shinichi
中科院分区：
文献类型：
--
作者：
Nozoe, Masafumi;Yamamoto, Miho;Shimada, Shinichi
背景：营养不良与中风患者的功能不良结果相关。然而，尚未报道根据全球营养不良领导倡议 (GLIM) 标准诊断的营养不良患病率或其与急性卒中患者日常生活活动 (ADL) 的关系。目的：调查急性脑卒中患者中根据 GLIM 标准诊断的营养不良患病率及其与 ADL 或出院目的地的关系。材料和方法：在这项横断面研究中，我们根据 GLIM 标准和欧洲临床营养与代谢学会 (ESPEN) 标准诊断营养不良，并通过功能独立测量运动域 (FIM-M) 评分评估急性卒中患者的 ADL。采用多变量回归分析来研究 FIM-M 评分或出院与 GLIM 或 ESPEN 标准定义的营养不良之间的关系。结果：共有 115 名急性脑卒中患者（39 名女性；中位年龄：72 岁）纳入本研究。根据 GLIM 标准和 ESPEN 标准，营养不良发生率分别为 28.7% 和 16.5%。调整潜在混杂因素后对 FIM-M 评分的多变量分析表明，GLIM 标准和 ESPEN 标准与 FIM-M 评分独立相关（分别为[3 =-0.238，p < 0.001；[3 =-0118，p = 0.040]）。对出院目的地的多变量分析发现，只有 GLIM 标准中的营养不良与出院显着相关（OR = 0.08，95% 置信区间 = 0.01-0.69，p = 0.02）。结论：符合 GLIM 标准的营养不良与 ADL 呈负相关，也与急性卒中的目的地相关。
Background: Malnutrition is associated with a poor functional outcome in patients with stroke. However, the prevalence of malnutrition diagnosed with the Global Leadership Initiative on Malnutrition (GLIM) criteria or its association with activity of daily living (ADL) in patients with acute stroke have not been reported. Objective: To investigate the prevalence of the malnutrition diagnosed with the GLIM criteria and its association with ADL or discharge destination in patients with acute stroke. Materials and methods: In this cross-sectional study, we diagnosed malnutrition with the GLIM criteria and the European Society for Clinical Nutrition and Metabo-lism (ESPEN) criteria and assessed ADL by functional independence measure motor domain (FIM-M) score in patients with acute stroke. Multivariate regression analysis was used to investigate the relationship between FIM-M score or home discharge and malnutrition defined with GLIM or ESPEN criteria. Results: A total of 115 acute stroke patients (39 females; median age: 72 years) were enrolled in this study. The prevalence of malnutrition according to GLIM-criteria and ESPEN-criteria was 28.7% and 16.5%, respectively. Multivariate analyses for FIM-M score after adjusting for potential confounders showed that GLIM criteria and ESPEN criteria were indepen-dently associated with FIM-M score ([3 =-0.238, p < 0.001; [3 =-0118, p = 0.040, respectively). A multivariate analysis for discharge destination found that only mal-nutrition from the GLIM criteria was significantly associated with home discharge (OR = 0.08, 95% confidential interval = 0.01-0.69, p = 0.02). Conclusions: Malnutrition with the GLIM criteria is negatively associated with ADL and is also associated with destination in with acute stroke.