Mortality and cause of death of Australians on the autism spectrum
Mortality and cause of death of Australians on the autism spectrum
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DOI：
10.1002/aur.2086
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发表时间：
2019-05-01
期刊：
影响因子：
4.7
通讯作者：
Trollor, Julian N.
中科院分区：
文献类型：
--
作者：
Hwang, Ye In (Jane);Srasuebkul, Preeyaporn;Trollor, Julian N.
关于自闭症人群的死亡率、危险因素和死亡原因的重点研究仍然很少。本研究使用2001年至2015年的大型关联数据集，报告了澳大利亚新南威尔士州自闭症谱系(年龄范围5-)中合并和不合并智力残疾(ID)的个人的死亡率和死亡原因的比率和危险因素。自闭症患者的死亡率是普通人群的2.06倍。同时患有ID、癫痫、精神健康状况和慢性身体健康状况的人死亡风险更高，而性别和社会经济地位等人口统计学变量则不相关。与普通人群相比，自闭症患者的主要死因存在差异，“神经系统和感觉障碍”以及“损伤和中毒”是导致自闭症患者死亡的最主要原因。这一发现提醒人们，有必要促进健康，并对自闭症患者同时存在的身心健康状况进行管理。还需要更好地识别、诊断和记录自闭症谱系中的老年人。自闭症研究2019，12：806-815。(C)2019年国际自闭症研究学会，Wiley期刊公司。
Focused investigations regarding mortality rates, risk factors, and cause of death in autistic populations remain scarce. The present study used large linked datasets spanning 2001-2015 to report the rates and risk factors for mortality and cause of death in individuals on the autism spectrum (n = 35,929 age range 5-64) with and without concurrent intellectual disability (ID) in New South Wales, Australia. Mortality rates for those on the autism spectrum were 2.06 times that of the general population. Concurrent ID, epilepsy, mental health conditions, and chronic physical health conditions were associated with a higher risk of death for those on the spectrum, whereas demographic variables such as gender and socioeconomic status were not. A differing profile of top causes of death was found for autistic individuals relative to the general population, with "nervous system and sense disorders" and "injury and poisoning" being the top-ranked causes for those on the spectrum. The findings alert the need for health promotion and management of concurrent physical and mental health conditions for those on the autism spectrum. There is also a need for better identification, diagnosis, and documentation of older adults on the autism spectrum. Autism Research 2019, 12: 806-815. (c) 2019 International Society for Autism Research, Wiley Periodicals, Inc.