Chikungunya Virus and Central Nervous System Infections in Children, India

Chikungunya Virus and Central Nervous System Infections in Children, India
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DOI:
10.3201/eid1502.080902
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发表时间:
2009-02-01
影响因子:
11.8
通讯作者:
Solomon, Tom
Solomon, Tom
中科院分区:
医学2区
文献类型:
--
作者:
Lewthwaite, Penny;Vasanthapuram, Ravi;Solomon, Tom

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基孔肯雅病毒 (CHIKV) 是一种蚊媒甲病毒,以引起发烧、皮疹、关节痛和偶尔的神经系统疾病而闻名。通过使用实时逆转录 PCR,我们在印度贝拉里 58 名疑似中枢神经系统感染儿童中的 8 名(14%)的血浆样本中检测到了 CHIKV。 3名儿童的脑脊液中也检测到了CHIKV。
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus best known for causing fever, rash, arthralgia, and occasional neurologic disease. By using real-time reverse transcription-PCR, we detected CHIKV in plasma samples of 8 (14%) of 58 children with suspected central nervous system infection in Bellary, India. CHIKV was also detected in the cerebrospinal fluid of 3 children.