Adjacent cationic-aromatic sequences yield strong electrostatic adhesion of hydrogels in seawater
Adjacent cationic-aromatic sequences yield strong electrostatic adhesion of hydrogels in seawater
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DOI：
10.1038/s41467-019-13171-9
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发表时间：
2019-11-12
影响因子：
16.6
通讯作者：
Gong, Jian Ping
中科院分区：
文献类型：
--
作者：
Fan, Hailong;Wang, Jiahui;Gong, Jian Ping
静电相互作用很强，但通常在高离子强度环境中减弱。即使在盐水培养基中，生物系统也可以通过蛋白质的邻近阳离子-芳香氨基酸序列利用这种相互作用。由于难以控制共聚物序列，将这种特定序列应用于盐碱环境中带负电荷表面的阳离子聚合物材料的开发具有挑战性。在这里，我们发现可以通过阳离子配合物辅助自由基聚合合成具有相邻阳离子-芳香序列的共聚物。不同阳离子/芳香单体的序列控制水凝胶对海水中带负电荷的表面具有快速、强且可逆的粘附性。共聚物上的芳烃被发现可以增强其相邻阳离子残基与计数器表面的静电相互作用，即使在屏蔽普通聚电解质静电相互作用的高离子强度介质中也是如此。这项工作为使用盐水开发粘合剂开辟了一条途径。
Electrostatic interaction is strong but usually diminishes in high ionic-strength environments. Biosystems can use this interaction through adjacent cationic-aromatic amino acids sequence of proteins even in a saline medium. Application of such specific sequence to the development of cationic polymer materials adhesive to negatively charged surfaces in saline environments is challenging due to the difficulty in controlling the copolymer sequences. Here, we discover that copolymers with adjacent cation-aromatic sequences can be synthesized through cation-ic complex-aided free-radical polymerization. Sequence controlled hydrogels from diverse cation/aromatic monomers exhibit fast, strong but reversible adhesion to negatively charged surfaces in seawater. Aromatics on copolymers are found to enhance the electrostatic interactions of their adjacent cationic residues to the counter surfaces, even in a high ionic-strength medium that screens the electrostatic interaction for common polyelectrolytes. This work opens a pathway to develop adhesives using saline water.