Sudden death due to acute pulmonary embolism in a young woman with COVID-19
Sudden death due to acute pulmonary embolism in a young woman with COVID-19
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DOI：
10.1007/s11239-020-02132-5
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发表时间：
2020-05-11
影响因子：
4
通讯作者：
Bostanci, Gungor Ilayda
中科院分区：
文献类型：
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作者：
Polat, Veli;Bostanci, Gungor Ilayda
2019年冠状病毒病(新冠肺炎)是一种主要影响呼吸系统的传染病，但可能会导致血栓栓塞症等心血管并发症。新冠肺炎感染严重的患者，特别是重症监护室的患者，很少会遇到肺栓塞。一例无症状的年轻新冠肺炎患者，因急性大面积肺栓塞而猝死，此病例以前未见过报道。我们报告一位41岁女性因在体力活动中猝死而到急诊科就诊。她只有糖尿病病史，在猝死前一直没有症状。CT肺血管造影和胸部CT扫描分别显示急性大面积栓塞和典型的新冠肺炎肺炎的影像表现。有趣的是，患者没有感染的症状或体征，也没有血栓栓塞症的危险因素。新冠肺炎感染似乎会导致静脉血栓栓塞症，特别是肺血栓栓塞症。这个案例值得注意的是，它展示了新冠肺炎感染的潜伏性和生命危害性。
Coronavirus disease 2019 (COVID-19) is an infectious disease that primarily affects the respiratory system, but it may cause cardiovascular complications such as thromboembolism. Rarely, pulmonary embolism may be encountered in patients with severe COVID-19 infection, especially in intensive care units. An asymptomatic young case of COVID-19 presenting with sudden death due to acute massive pulmonary embolism has not been previously described. We report a 41-year-old woman presented to emergency department with sudden death during physical activity. She had only history of diabetes mellitus and she was asymptomatic until sudden death. CT pulmonary angiography and chest CT scans revealed acute massive embolism and typical imaging findings of COVID-19 pneumonia, respectively. Interestingly, the patient had no symptoms or signs of infection and also had no risk factors for thromboembolism. COVID-19 infection appears to induce venous thromboembolism, especially pulmonary embolism. The case is remarkable in terms of showing how insidious and life-threatening COVID-19 infection can be.