Immunization with recombinant surface antigen P50 of Babesia gibsoni expressed in insect cells induced parasite growth inhibition in dogs

Immunization with recombinant surface antigen P50 of Babesia gibsoni expressed in insect cells induced parasite growth inhibition in dogs
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DOI:
10.1128/cdli.12.4.557-559.2005
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发表时间:
2005-04-01
期刊:
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY
影响因子:
--
通讯作者:
Xuan, XN
Xuan, XN
中科院分区:
其他
文献类型:
--
作者:
Fukumoto, S;Tamaki, Y;Xuan, XN

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这是一份使用重组抗原P50在犬中进行的针对吉氏巴氏巴氏杆菌感染的疫苗试验报告。用P50免疫的狗表现出部分保护,表现为显著低水平的寄生虫血症。结果表明,P50是抗犬B的主要疫苗候选分子。Gibsoni感染
This is a report of a vaccine trial directed against Babesia gibsoni infection in dogs with the use of the recombinant antigen P50. Dogs immunized with P50 showed partial protection manifested as a significantly low level of parasitemia. The results indicated that P50 is a primary vaccine candidate molecule against canine B. gibsoni infection.