The single-step synthesis of a DNA tetrahedron
The single-step synthesis of a DNA tetrahedron
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DOI：
10.1039/b402293a
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发表时间：
2004-06-21
影响因子：
4.9
通讯作者：
Turberfield, AJ
中科院分区：
文献类型：
--
作者：
Goodman, RP;Berry, RM;Turberfield, AJ
当四种经过适当设计的寡核苷酸在溶液中退火结合在一起时，一种边缘为DNA双螺旋的四面体纳米结构会自发地自组装；这种构建体易于合成、具有刚性且适应性强，使其成为容纳其他大分子的笼子以及构建更复杂纳米结构的有希望的候选材料。
A tetrahedral nanostructure whose edges are DNA double helices self-assembles spontaneously when four appropriately designed oligonucleotides are annealed together in solution; the ease of synthesis, rigidity, and adaptability of this construct make it a promising candidate as a cage for other large molecules and as a building block for more complicated nanostructures.