Epidemiology of hepatocellular carcinoma: consider the population.

Epidemiology of hepatocellular carcinoma: consider the population.
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DOI:
10.1097/mcg.0b013e3182872f29
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发表时间:
2013-07
影响因子:
2.9
通讯作者:
El-Serag HB
El-Serag HB
中科院分区:
医学3区
文献类型:
--
作者:
Mittal S;El-Serag HB

文献摘要

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肝细胞癌(HCC)的发病率正在增加,并且具有非常高的病死率。慢性B型肝炎或丙型肝炎引起的肝硬化是HCC的主要危险因素。HCC的全球流行病学由显性病毒性肝炎的患病率和基础人群中获得的年龄决定。即将到来的风险因素包括肥胖、糖尿病和相关的非酒精性脂肪肝。本综述讨论了全球和美国HCC的最新趋势。它还提供了一个基于证据的评论的危险因素,并列出了一些预防措施,以减少肝癌的发病率。
Hepatocellular carcinoma (HCC) is increasing in incidence and has a very high fatality rate. Cirrhosis due to chronic hepatitis B or hepatitis C is the leading risk factor for HCC. Global epidemiology of HCC is determined by prevalence of dominant viral hepatitis and the age it is acquired in the underlying population. Upcoming risk factors include obesity, diabetes and related non-alcoholic fatty liver disease. This review discusses the latest trends of HCC globally and in the United States. It also provides an evidence-based commentary on the risk factors and lists some preventive measures to reduce the incidence of HCC.