Heteroacene Synthesis through C-S Cross-Coupling/5-endo-dig Cyclization.
Heteroacene Synthesis through C-S Cross-Coupling/5-endo-dig Cyclization.
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DOI：
10.1002/chem.201603737
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发表时间：
2016-12
期刊：
影响因子：
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通讯作者：
P. Oechsle;U. Flörke;Hans Egold;J. Paradies
中科院分区：
文献类型：
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作者：
P. Oechsle;U. Flörke;Hans Egold;J. Paradies
通过钯催化双炔与硫代乙酸酯作为硫化氢替代物的 C-S 交叉偶联，实现了含硫杂并苯的高效一步合成。通过形成四、六和八重C-S键，在单一催化步骤中获得由三、五和七个稠合芳环组成的杂并苯。
Highly efficient, one-step synthesis of sulfur-containing heteroacenes was achieved through palladium-catalyzed C-S cross-coupling of bis-alkynes with thioacetate as hydrogen sulfide surrogate. Heteroacenes consisting of three, five, and seven fused aromatic rings were obtained in a single catalytic step by four-, six-, and eightfold C-S bond formation.