Hippocampal volume and declarative memory function in combat-related PTSD.

Hippocampal volume and declarative memory function in combat-related PTSD.
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战斗相关创伤后应激障碍中的海马体积和陈述性记忆功能。

DOI:
10.1017/s1355617709990476
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发表时间:
2009
期刊:
Journal of the International Neuropsychological Society : JINS
影响因子:
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通讯作者:
Eliez,Stephan
Eliez,Stephan
中科院分区:
--
文献类型:
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作者:
Woodward,StevenH;Kaloupek,DannyG;Grande,LauraJ;Stegman,WendyK;Kutter,CatherineJ;Leskin,Loraine;Prestel,Rebecca;Schaer,Marie;Reiss,AllanL;Eliez,Stephan

文献摘要

相似文献

陈述性记忆缺陷与较小的海马体积系统相关的命题在相对较大的样本(n = 95)中进行了测试美国退伍军人有和没有战斗相关的创伤后应激障碍。这种相关性分析通过包括言语和视觉陈述性记忆的多项测量以及在先前工作中已显示出PTSD主要影响的多个记忆相关区域脑体积来扩展。根据最近的荟萃分析,观察到对口头陈述性记忆的小到中度影响;然而,很少或没有证据表明记忆测量和脑容量之间存在系统性线性协变。(JINS,2009,15,830-839.)
The proposition that declarative memory deficits are systematically related to smaller hippocampal volume was tested in a relatively large sample (n = 95) of U.S. military veterans with and without combat-related posttraumatic stress disorder. This correlative analysis was extended by including multiple measures of verbal and visual declarative memory and multiple memory-relevant regional brain volumes that had been shown to exhibit main effects of PTSD in prior work. Small-to-moderate effects were observed on verbal declarative memory in line with a recent meta-analysis; nevertheless, little or no evidence of systematic linear covariation between memory measures and brain volumes was observed. (JINS, 2009, 15, 830–839.)