Nucleotide-stabilized cadmium sulfide nanoparticles
Nucleotide-stabilized cadmium sulfide nanoparticles
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DOI：
10.1039/b616306h
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发表时间：
2007-01-01
影响因子：
--
通讯作者：
Kelley, Shana O.
中科院分区：
文献类型：
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作者：
Dooley, Chad J.;Rouge, Jessica;Kelley, Shana O.
研究了由天然和非天然的5 '-核苷酸三磷酸稳定的硫化镉纳米颗粒，以阐明在发射材料的合成中涉及的特定化学功能。利用光致发光光谱、透射电子显微镜和琼脂糖凝胶电泳对核碱基官能团在半导体晶体合成中的作用进行了解卷积。通过对所有天然核苷的调查，发现5 '-鸟苷三磷酸最有效地稳定发射性纳米颗粒，而腺苷、肌苷、胞苷、尿嘧啶和7-甲基鸟苷核碱基除非在碱性条件下使用，否则不能促进发射性产物的成功合成。所提出的工作系统地探索和鉴定了可用于生产水溶性半导体纳米晶体的多核酸内的重要功能。
Cadmium sulfide nanoparticles stabilized by both natural and unnatural 5'-nucleotide triphosphates were investigated to elucidate the specific chemical functionalities involved in the synthesis of emissive materials. The roles of the nucleobase functionalities in semiconductor nanocrystal synthesis are deconvoluted using photoluminescence spectroscopy, transmission electron microscopy and agarose gel electrophoresis. Through a survey of all the natural nucleosides, it was discovered that 5'-guanosine triphosphate most effectively stabilizes emissive nanoparticles, while adenosine, inosine, cytidine, uracil and 7-methylguanosine nucleobases do not facilitate successful synthesis of emissive product unless used under basic conditions. The work presented systematically explores and identifies important functionalities within polynucleic acids that can be used to produce aqueous soluble semiconductor nanocrystals.