Diclofenac sodium, diflunisal and naproxen: patient preferences for anti-inflammatory drugs in rheumatoid arthritis.
Diclofenac sodium, diflunisal and naproxen: patient preferences for anti-inflammatory drugs in rheumatoid arthritis.
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双氯芬酸钠、二氟尼柳和萘普生：类风湿性关节炎患者对抗炎药物的偏好。
DOI：
10.1093/rheumatology/21.4.238
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
H. Jones
中科院分区：
文献类型：
--
作者：
E. Huskisson;P. Dieppe;J. Scott;H. Jones
90例活动性类风湿关节炎患者参加了一项交叉试验，比较双氯芬酸钠、二氟尼柳和萘普生。三种药物的疗效相似，尽管在某些测量中存在有利于双氯芬酸钠的趋势。三种药物的副作用发生率相似，并且在研究结束时，每种药物都被一组重要的患者选择作为继续治疗。
Ninety patients with active rheumatoid arthritis took part in a cross-over trial comparing diclofenac sodium, diflunisal and naproxen. The efficacy of the three drugs was similar though there were trends in favour of diclofenac sodium in some measurements. The incidence of side-effects was similar with the three drugs and each was chosen by a significant group of patients as continuation therapy at the end of the study.