Two New Flavonoids fromDerris eriocarpaHow
Two New Flavonoids fromDerris eriocarpaHow
复制标题
DOI：
10.1002/hlca.201500247
复制
发表时间：
2016-04
影响因子：
1.8
通讯作者：
Hua-yong Lou;Hong‐Guo Wu;Yonghua Tan;J. Lan;Xiao-Pan Ma;Guang-yi Liang;Ping Yi;W. Pan
中科院分区：
文献类型：
--
作者：
Hua-yong Lou;Hong‐Guo Wu;Yonghua Tan;J. Lan;Xiao-Pan Ma;Guang-yi Liang;Ping Yi;W. Pan
Two new flavonoids, 1 and 2, together with two known flavonoids, tephrosin (3) and 12a-hydroxy-α-toxicarol (4), were isolated from the whole herb of Derris eriocarpa How. The structures and absolute configurations of the new compounds were elucidated on the basis of their MS, NMR, and ECD data. The structures of the known compounds were established by extensive spectroscopic (MS, 1D- and 2D-NMR) analyses and comparison with the literature data. All compounds were isolated from D. eriocarpa for the first time. Compound 3 showed modest inhibitory activities against the growth of human cancer cells HEL and A549 with the IC50 values of 15.03 ± 0.62 and 13.27 ± 0.39 μm, respectively.
