Natural occurrence of 2-5A in interferon-treated EMC virus-infected L cells
Natural occurrence of 2-5A in interferon-treated EMC virus-infected L cells
复制标题
干扰素处理的 EMC 病毒感染的 L 细胞中自然出现 2-5A
作者：
B. Williams;R. R. Golgher;R. R. Golgher;Ronald E. Brown;Christopher S. Gilbert;I. M. Kerr
迄今为止，尚未在完整细胞中检测到介导的2′-5′腺嘌呤寡核苷酸抑制剂（2-5A）。在这里，我们报告他们的自然发生在干扰素处理，EMC病毒感染的小鼠L细胞的数量一致的想法，他们发挥了抑制病毒生长的一部分。
Until now the inierfer on-mediated 2′–5′ adenine oligonucleotide inhibitors (2–5A) of cell-free protein synthesis have not been detected in intact cells. Here we report their natural occurrence in interferon-treated, EMC virus-infected mouse L cells in amounts consistent with the idea that they play a part in the inhibition of virus growth.