Positron-Emission Tomography Quantitative Measurements of Myocardial Blood Flow: Just the Facts….

Positron-Emission Tomography Quantitative Measurements of Myocardial Blood Flow: Just the Facts….
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心肌血流的正电子发射断层扫描定量测量:事实......

DOI:
10.1016/j.jcmg.2019.03.035
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发表时间:
2019
期刊:
JACC. Cardiovascular imaging
影响因子:
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通讯作者:
H. Schelbert
H. Schelbert
中科院分区:
--
文献类型:
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作者:
H. Gewirtz;A. Iskandrian;C. Morgan;H. Schelbert

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大多数PET定量MBF检查用于评估已知或疑似冠状动脉疾病(CAD)(1)。另一个常见的适应症是微循环的评估,特别是在非典型胸痛综合征患者中(2,3)。弥漫性导管血管疾病也可能存在于CAD背景中,并将导致总生理负担,导管和微血管水平的内皮功能障碍也会导致总生理负担(3-6)。将这些实体分开可能是不可能的,因为所有这些实体通常都存在于冠状动脉粥样硬化的背景中(4,5)。
Most PET quantitative MBF exams are performed for evaluation of known or suspected coronary artery disease (CAD)(1). Another common indication is evaluation of the microcirculation, particularly in patients with atypical chest pain syndromes (2, 3). Diffuse conduit vessel disease also may be present in the setting of CAD and will contribute to the total physiological burden as will endothelial dysfunction at both conduit and microvascular levels(3–6). Teasing apart these entities may not be possible because all are typically present in the setting of coronary atherosclerosis (4, 5).
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