TOPOGRAPHY OF VISUAL AND SOMATOSENSORY PROJECTIONS TO MOUSE SUPERIOR COLLICULUS
TOPOGRAPHY OF VISUAL AND SOMATOSENSORY PROJECTIONS TO MOUSE SUPERIOR COLLICULUS
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DOI：
10.1152/jn.1976.39.1.91
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发表时间：
1976-01-01
影响因子：
2.5
通讯作者：
HUBEL, DH
中科院分区：
文献类型：
--
作者：
DRAGER, UC;HUBEL, DH
在C57 BL/6 J品系的成年小鼠中，在直视下系统地绘制了视野的投影。与其他脊椎动物一样，鼻（前）野投射在前外侧，而下野投射在后外侧。在冠状面和矢状面的测量中，计算大部分顶盖的放大率-1（m-1，或每毫米顶盖表面的视野度）。而m-1是相当恒定的测量对矢状面，冠状面有一个相当大的，细长的，水平方向的区域在上视野内的m-1是小于其他地方。在这一领域的m-1是各向异性的，矢状面和冠状面之间的比例几乎为2：1。在先前的研究中，我们观察到许多记录在更深的顶盖层的细胞对躯体感觉刺激做出反应，胡须特别明显。在垂直于顶盖表面的特定穿透中，记录在更深顶盖中的体感感受野总是与那组胡须有关，或者与穿过直接在上面的浅层中代表的视野区域的身体部位有关。鉴于与某些躯体感觉场相关的视觉坐标信息，将视野详细映射到顶盖上，就有可能绘制出顶盖上躯体感觉投射的地图。由此产生的代表性显着不同的地图描述的经典躯体感觉通路。在顶盖的躯体感觉地图是由视觉领域的投影，而不是由周边触觉神经支配密度。因此，胡须在顶盖中显得更加突出，而靠近眼睛的结构，例如耳廓和脸颊，比尾巴或后爪得到更多的代表。
In adult mice of the C57BL/6J strain the projection of the visual field was systematically mapped under direct vision. As in other vertebrate species the nasal (anterior) field projected anterolaterally, and the inferior field posterolaterally. Values of magnification-1 (m-1, or degrees of visual field per millimeter tectal surface) were calculated over most of the tectum, for measurements in the coronal and sagittal planes. Whereas m-1 was fairly constant for measurement pairs in sagittal planes, for coronal planes there was a rather large, elongated, horizontally oriented area in the upper field of vision within which m-1 was smaller than elsewhere. In this area m-1 was anisotropic, with a ratio of almost 2:1 between sagittal and coronal planes. In a previously study we had observed that many cells recorded in deeper tectal layers responded to somatosensory stimulation, with whiskers especially conspicuous. In a given penetration perpendicular to the tectal surface, somatosensory receptive fields recorded in the deeper tectum were always concerned with that group of whiskers or with those parts of the body that crossed the regions of visual field represented in the superficial layers directly above. Given this information on the visual coordinates associated with certain somatosensory fields, the detailed mapping of the visual field onto the tectum made it possible to prepare a map of the somatosensory projection on the tectum. The resulting representation differed markedly from maps described for the classic somatosensory pathway. In the tectum the somatosensory map was dictated by the visual-field projection rather than by the peripheral tactile innervation density. Whiskers were thus featured much more prominently in the tectum, and structures close to the eye, such as the pinna and cheek, receive more representation than the tail or hindpaws.