Bayesian optimisation for efficient parameter inference in a cardiac mechanics model of the left ventricle.
Bayesian optimisation for efficient parameter inference in a cardiac mechanics model of the left ventricle.
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DOI:
10.1002/cnm.3593
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发表时间:
2022-05
影响因子:
2.1
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中科院分区:
文献类型:
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We consider parameter inference in cardio‐mechanic models of the left ventricle, in particular the one based on the Holtzapfel‐Ogden (HO) constitutive law, using clinical in vivo data. The equations underlying these models do not admit closed form solutions and hence need to be solved numerically. These numerical procedures are computationally expensive making computational run times associated with numerical optimisation or sampling excessive for the uptake of the models in the clinical practice. To address this issue, we adopt the framework of Bayesian optimisation (BO), which is an efficient statistical technique of global optimisation. BO seeks the optimum of an unknown black‐box function by sequentially training a statistical surrogate‐model and using it to select the next query point by leveraging the associated exploration‐exploitation trade‐off. To guarantee that the estimates based on the in vivo data are realistic also for high‐pressures, unobservable in vivo, we include a penalty term based on a previously published empirical law developed using ex vivo data. Two case studies based on real data demonstrate that the proposed BO procedure outperforms the state‐of‐the‐art inference algorithm for the HO constitutive law.
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影响因子:
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DOI:
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DOI:
10.1098/rsif.2017.0203
发表时间:
2017-07
期刊:
Journal of the Royal Society, Interface
影响因子:
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作者:
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通讯作者:
Berry C
DOI:
10.32604/mcb.2019.07364
发表时间:
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期刊:
Molecular & cellular biomechanics : MCB
影响因子:
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作者:
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通讯作者:
Guccione, Julius M