CIN-like TCP Transcription Factors: The Key Regulators of Plant Development and Immunity
CIN-like TCP Transcription Factors: The Key Regulators of Plant Development and Immunity
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CIN 样 TCP 转录因子：植物发育和免疫的关键调节因子
DOI：
10.16476/j.pibb.2017.0012
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发表时间：
2017
影响因子：
0.3
通讯作者：
Huxin Hu
中科院分区：
文献类型：
--
作者：
Zhicai Wang;Dayong Cui;Huxin Hu
根据共有的bHLH TCP结构域，植物特异性TEOSINTE BRANCHED 1、CYCLOIDEA和PCF（TCP）转录因子分为两类，I类和II类TCP。越来越多的证据表明，一类II类CINCINNATA-like（CIN-like）TCP转录因子通过调节激素的生物合成和信号传导在植物构型的建立中起着重要作用。最近的研究表明，它们在介导病原性效应子触发免疫（ETI）中发挥了意想不到的作用，表明广泛认可的发育调节剂也参与了植物免疫的微调。尽管对CIN样TCP蛋白的调控途径的研究已经开始揭示其作用机制，但迫切需要基于现有信息的统一和更新的观点。本文综述了CIN样TCP在各种调控级联中的功能及其作为效应靶点的作用，重点介绍了其突变体、TCP相互作用因子和相互关联的激素网络的特征。并对这些蛋白的研究前景进行了展望。
The plant-specific TEOSINTE BRANCHED1, CYCLOIDEA, and PCF (TCP) transcription factors are classified into two.classes, class I and class II TCPs according to the shared bHLH TCP domain. Accumulating evidences demonstrate that a subgroup.of class II CINCINNATA-like (CIN-like) TCP transcription factors plays a vital role in the establishment of plant architecture through.modulating hormone biosynthesis and signaling. Recent advances have revealed their unexpected roles in mediating pathogenic.effectors-triggered immunity (ETI), suggesting that the widely recognized developmental modulators are involved in fine-tuning plant.immunity as well. Although the dissection of the regulatory pathway of CIN-like TCP proteins has begun to shed light on their.mechanismof action, a unified and updated view based on the available information is urgently needed. This review aims to summarize.the current knowledge about the functions of CIN-like TCPs in various regulatory cascades, and their roles as effector targets with an.emphasis on the characterization of the available mutants, TCP interacting factors and the interconnected hormonal networks. Future.perspectives for the research of these proteins are also discussed.