Course of cytomegalovirus retinitis in the era of highly active antiretroviral therapy - 2. Second eye involvement and retinal detachment
Course of cytomegalovirus retinitis in the era of highly active antiretroviral therapy - 2. Second eye involvement and retinal detachment
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DOI：
10.1016/j.ophtha.2004.05.028
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发表时间：
2004-12-01
期刊：
影响因子：
13.7
通讯作者：
Li, HK
中科院分区：
文献类型：
--
作者：
Jabs, DA;Van Natta, ML;Li, HK
目的：描述艾滋病患者在高效抗逆转录病毒治疗（HAART）时代的巨细胞病毒（CMV）视网膜炎病程。设计：多中心、前瞻性、观察性研究。参与者：271例艾滋病和CMV视网膜炎患者。方法：每3个月随访一次，包括病史、眼科检查、实验室检查和眼底照片。主要结果测量：结果：单侧CMV视网膜炎患者第二眼受累的总体发生率为0.07/人年（PY）;在CD 4 + T细胞计数为
Purpose: To describe the course of cytomegalovirus (CMV) retinitis in patients with AIDS in the era of highly active antiretroviral therapy (HAART).Design: Multicenter, prospective, observational study.Participants: Two hundred seventy-one patients with AIDS and CMV retinitis.Methods: Follow-up every 3 months with medical history, ophthalmologic examination, laboratory testing, and fundus photographs.Main Outcome Measure: Second (contralateral) eye involvement among patients with unilateral disease and retinal detachment (RD).Results: The overall rate of second eye involvement among patients with unilateral CMV retinitis was 0.07 per person-year (PY); among those with CD4+ T-cell counts of