Evaluation of the dual route theory of reading: a metanalysis of 35 neuroimaging studies
Evaluation of the dual route theory of reading: a metanalysis of 35 neuroimaging studies
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DOI：
10.1016/s1053-8119(03)00343-4
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发表时间：
2003-10-01
期刊：
影响因子：
5.7
通讯作者：
Tzourio-Mazoyer, N
中科院分区：
文献类型：
--
作者：
Jobard, G;Crivello, F;Tzourio-Mazoyer, N
过去十年中，发表了许多有关单词阅读背后的大脑结构的研究。一些争议。然而。加上实验室之间的方法或理论差异，仍然导致神经影像学进步的整体观点变得模糊。在双重阅读框架内进行的荟萃分析的目的是提供这些进展的客观描述。为了实现这一目标，我们使用了一种自动分析方法，该方法基于 35 项已发表的神经影像研究的单词或伪单词阅读对比所发出的激活峰值清单。这项荟萃分析的第一个结果是，没有发现比伪词阅读更多的单词激活簇，这意味着单词访问的第一步可能对单词和类似单词的刺激是常见的，并且会发生在位于腹侧路线、颞下回和梭状回交界处的左枕颞区（以前称为视觉单词形式区-VWFA）内。结果还表明，大脑区域的存在主要涉及两种获取单词的途径之一。字音转换似乎确实依赖于左侧脑结构，例如颞上区、边缘上回和额下回的盖部，这最后两个区域反映了在这种访问过程中工作记忆的更大负荷。词汇语义路径被认为是由 VWFA 和语义区域的共同激活产生的。这些语义区域将涵盖基底颞下区、颞中回的后部和额下回的三角形部分。这些结果证实了双途径框架适用于解释在非病理受试者阅读时观察到的激活。 (C) 2003 Elsevier Inc. 保留所有权利。
Numerous studies concerned with cerebral structures underlying word reading have been published during the last decade. A few controversies. however. together with methodological or theoretical discrepancies between laboratories, still contribute to blurring the overall view of advances effected in neuroimaging. Carried out within the dual route of reading framework, the aim of this metanalysis was to provide an objective picture of these advances. To achieve this, we used an automated analysis method based on the inventory of activation peaks issued from word or pseudoword reading contrasts of 35 published neuroimaging studies. A first result of this metanalysis was that no cluster of activations has been found more recruited by word than pseudoword reading, implying that the first steps of word access may be common to word and word-like stimuli and would take place within a left occipitotemporal region (previously referred to as the Visual Word Form Area-VWFA) situated in the ventral route, at the junction between inferior temporal and fusiform gyri. The results also indicated the existence of brain regions predominantly involved in one of the two routes to access word. The graphophonological conversion seems indeed to rely on left lateralized brain structures such as superior temporal areas, supramarginal gyrus, and the opercular part of the inferior frontal gyrus, these last two regions reflecting a greater load in working memory during such an access. The lexicosemantic route is thought to arise from the coactivation of the VWFA and semantic areas. These semantic areas would encompass a basal inferior temporal area, the posterior part of the middle temporal gyrus, and the triangular part of inferior frontal gyrus. These results confirm the suitability of the dual route framework to account for activations observed in nonpathological subjects while they read. (C) 2003 Elsevier Inc. All rights reserved.