THE EFFECT OF LOCAL-ANESTHESIA OF THE NASAL VESTIBULE ON NASAL SENSATION OF AIR-FLOW AND NASAL RESISTANCE
THE EFFECT OF LOCAL-ANESTHESIA OF THE NASAL VESTIBULE ON NASAL SENSATION OF AIR-FLOW AND NASAL RESISTANCE
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DOI：
10.1111/j.1365-2273.1987.tb00233.x
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发表时间：
1987-12-01
影响因子：
2.1
通讯作者：
BECKINGHAM, E
中科院分区：
文献类型：
--
作者：
JONES, AS;CROSHER, R;BECKINGHAM, E
在15名受试者中评估了鼻前庭局部麻醉对鼻气流感觉和鼻阻力的影响。采用单盲平行组试验，以木黄酮为活性药物，生理盐水为安慰剂，对30例受试者进行治疗。每组包括15名受试者。两种药物均通过唇下途径双侧浸润至每侧鼻前庭底部。15例受试者中9例用浸润性木质素局部麻醉鼻前庭，产生鼻塞感（P < 0.02）。生理盐水浸润则无此作用。两种药物对鼻气流感觉的影响差异有显著性（P < 0.05）。通过主动前鼻孔测压法评估，两种注射液对鼻气流阻力均无显著影响。
The effect of local anaesthesia of the nasal vestibule on nasal sensation of airflow and nasal resistance was assessed in 15 subjects. A single blind parallel group trial was undertaken in 30 subjects, with lignocaine as the active drug, and normal saline as the placebo. Fifteen subjects were included in each group. Both agents were infiltrated bilaterally into the floor of the nasal vestibule on each side via the sublabial route. Local anaesthesia of the nasal vestibule by infiltrating lignocaine produced a sensation of nasal obstruction in 9 out of 15 subjects (P < 0.02). The infiltration of normal saline had no such effect. The difference between the effect of the 2 agents on nasal airflow sensation was significant (P < 0.05). Neither injection had any significant effect on nasal resistance to airflow as assessed by active anterior rhinomanometry.