A pattern to regenerate through turnover
A pattern to regenerate through turnover
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DOI：
10.1016/j.biosystems.2012.08.001
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发表时间：
2012-10-01
期刊：
影响因子：
1.6
通讯作者：
Yoshida, Hiroshi
中科院分区：
文献类型：
--
作者：
Yoshida, Hiroshi
动植物的组织是通过平衡的细胞生长、运动和消除来维持的。虽然细胞是永久交换的，但组织的整个结构仍保持不变。这种维护形式被称为细胞周转。在这里，我提出了一个受生物启发的模式模型，它通过人员更替而再生。这个模型是从Dachsous-Fat系统衍生而来的，该系统最近引起了很大的关注，因为它被认为有助于昆虫腿的再生。在这个模型中，我对细胞分裂过程中腊肠和脂肪的再分配方式进行了参数化，并推导出了使模式在周转过程中能够再生和自我维持的参数方程。我将一维模型中推导出的方程推广到二维模型。最后，我讨论了再生和人员流动之间可能存在的关系。(C)2012爱思唯尔爱尔兰有限公司。保留所有权利。
Tissues of animals and plants are maintained through balanced cell growth, movement, and elimination. Although cells are exchanged perpetually, the whole structure of the tissue is maintained. This form of maintenance is called cell turnover. Here I propose a bio-inspired model of patterns that regenerate through turnover. This model is derived from the Dachsous-Fat system, which has recently attracted much attention because it is considered to facilitate regeneration in insect legs. In this model, I parameterized the manner of the redistribution of Dachsous and Fat during cell division, and then derived equations in the parameters that enable the patterns to regenerate and maintain themselves through turnover. I extended the equations derived in the one-dimensional model into a two-dimensional model. Finally, I discuss a possible relationship between regeneration and turnover. (C) 2012 Elsevier Ireland Ltd. All rights reserved.