Acquisition and extended retention of a conditioned taste aversion in preweanling rats.
Acquisition and extended retention of a conditioned taste aversion in preweanling rats.
复制标题
断奶前大鼠条件性味觉厌恶的获得和延长保留。
DOI：
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发表时间：
1982
期刊：
影响因子：
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通讯作者：
L. Green
中科院分区：
文献类型：
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作者：
L. Schweitzer;L. Green
幼年大鼠记忆衰退的时间过程可能会揭示婴儿期健忘症的过程。本研究采用一种适用于新生大鼠和成年大鼠的味觉厌恶条件反射程序，通过四个实验探讨了延长记忆保留的个体发生。在实验1中，测试在1、10、20或60日龄训练的大鼠25天后的味觉厌恶保持情况。在测试中，只有那些在20或60天大的大鼠表现出明显的味觉厌恶。实验2和3确定，14-15日龄和更大的大鼠能够在25天的保留间隔后保留显著的味觉厌恶。然而，年轻的大鼠确实获得并保留了几天的厌恶，并在逐渐延长的保留时间间隔内表现出逐渐的保留损失（实验4）。这些研究结果表明，断奶前大鼠表现出初步的巩固，存储和检索条件性味觉厌恶。只有在这个初始阶段之后，保留赤字才变得明显。
The time course of memory decay for infant rats may shed light on the processes responsible for infantile amnesia. A taste aversion conditioning procedure appropriate for both neonatal and adult rats was employed in four experiments to investigate the ontogeny of extended retention. In Experiment 1, rats trained at 1, 10, 20, or 60 days of age were tested for retention of the taste aversion 25 days later. At testing, only those rats conditioned when 20 or 60 days old demonstrated significant taste aversions. Experiments 2 and 3 established that rats 14-15 days old and older were able to retain significant taste aversions following a 25-day retention interval. Younger rats did, however, acquire and retain the aversion for several days and showed a gradual retention loss over progressively longer retention intervals (Experiment 4). These findings suggest that preweanling rats demonstrate initial consolidation, storage, and retrieval of conditioned taste aversions. It is only after this initial period that retention deficits become evident.