Sex differentiation during the early pouch stages of the opossum (Didelphys virginiana) and a comparison of the anatomical changes induced by male and female sex hormones

Sex differentiation during the early pouch stages of the opossum (Didelphys virginiana) and a comparison of the anatomical changes induced by male and female sex hormones
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负鼠(Didelphys virginiana)早期育儿袋阶段的性别分化以及雄性和雌性性激素引起的解剖变化的比较

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发表时间:
1939
期刊:
影响因子:
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通讯作者:
R. Burns
R. Burns
中科院分区:
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文献类型:
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作者:
R. Burns

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在最近的一篇论文(伯恩斯,'39 d)中,描述了雄激素丙酸睾丸酮对袋状幼体负鼠生殖道发育的影响。该帐户主要处理的解剖顺序的变化,诱导老年实验组,治疗后的40至50天的持续时间。对各部分的详细组织学描述保留以供单独发表;仅提供必要的组织学数据,以验证解剖学发现并确定各种结构的范围和连续性。研究发现,丙酸睾酮在较大剂量时,对两性胚胎生殖器官的适当部位既有促雄激素作用,又有促雌激素作用。也就是说(除了一个重要的例外),两性的完整导管系统及其衍生物通常都存在于任何一种遗传性别的个体中,并且是早熟发育的;而阴茎则非常肥大,在形式上具有男性的特征。这些影响是合格的定量
In a recent paper (Burns, '39 d ) the effects of the androgen testosterone propionate on the developing reproductive tracts in pouch young of the opossum were described. This account dealt primarily with changes of an anatomical order induced in older experimental groups, after treatment of 40 to 50 days duration. Detailed histological descriptions of the various parts were reserved f o r separate publication; only such histological data being given as were necessary to verify the anatomical findings and establish the extent and continuity of the various structures. It was found that testosterone propionate, in comparatively large doses, has both an androgenic and a gynogenic action upon appropriate parts of the reproductive apparatus in embryos of both sexes. That is (with one important exception) complete duct systems of both sexes, and their derivatives, are typically present and precociously developed in individuals of either genetic sex ; while the phallus is greatly hypertrophied and characteristically male in form. These effects are qualified in a quantitative