The effects and effectiveness of laparoscopic excision of endometriosis: a prospective study with 2-5 year follow-up

The effects and effectiveness of laparoscopic excision of endometriosis: a prospective study with 2-5 year follow-up
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DOI:
10.1093/humrep/deg275
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发表时间:
2003-09-01
期刊:
影响因子:
6.1
通讯作者:
Garry, R
Garry, R
中科院分区:
医学1区
文献类型:
--
作者:
Abbott, JA;Hawe, J;Garry, R

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背景:本研究调查了腹腔镜子宫内膜异位症切除术后5年的结局。研究方法:在这项前瞻性观察性队列研究中,254名患有慢性盆腔疼痛的妇女被转诊到两个专门从事子宫内膜异位症微创手术治疗的单位。其中,216名妇女接受了手术评估,176名被证实患有子宫内膜异位症。术前完成了排尿困难、非月经性盆腔痛、性交困难和排便困难的量表和视觉模拟量表(VAS)评分以及生活质量量表; EQ-5D指数和EQ-5Dvas、简明12量表(SF-12)和性活动问卷。术中详细记录了修订的美国生育协会(rAFS)分期、疾病部位、相关检查、手术持续时间和并发症。通过邮寄问卷和图表审查进行随访。对于接受进一步手术的女性,记录rAFS分期、疾病部位、其他手术和组织学。结果:2-5年时,排尿困难的疼痛评分均显著降低(VAS基线与随访2-5年时的中位数); 9分与3.3分(P
Background: This study investigates the outcomes for women up to 5 years after laparoscopic excision of endometriosis. Methods: In this prospective observational cohort study, 254 women with chronic pelvic pain were referred to two units specializing in minimal access surgical management of endometriosis. Of these, 216 women underwent surgical assessment and 176 were confirmed to have endometriosis. Questionnaires and visual analogue scale (VAS) scores for dysmenorrhoea, non-menstrual pelvic pain, dyspareunia and dyschesia as well as quality of life instruments; the EQ-5Dindex and EQ-5Dvas, Short-Form 12 (SF-12) and sexual activity questionnaires were completed pre-operatively. Intra-operative details of revised American Fertility Society (rAFS) stage, site of disease, associated tests, duration of surgery and complications were noted. Follow-up was performed by postal questionnaire and chart review. For women who had further surgery, rAFS stage, site of disease, other procedures and histology were all recorded. Results: Pain scores were all significantly reduced at 2-5 years for dysmenorrhoea (median VAS baseline versus follow-up 2-5 years); 9 versus 3.3 (P