Synthesis and degradation of liver metallothionein.
Synthesis and degradation of liver metallothionein.
复制标题
肝脏金属硫蛋白的合成和降解。
DOI：
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发表时间：
1979
期刊：
影响因子：
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通讯作者：
R. Cousins
中科院分区：
文献类型：
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作者：
R. Cousins
The function of metallothionein has been debated for years. However, now it is clear that at least one of its roles is in hepatic zinc metabolism. In the liver, metallothionein appears to be related to the mechanism of zinc uptake into hepatocytes and may function as a binding ligand to help regulate the intracellular concentration of free zinc ions (1). Therefore, since the dietary intake of zinc is variable and zinc metabolism at the cellular level is dynamic, it is reasonable to assume that metallothionein is subject to changes in synthesis and degradation in response to zinc status.
