Parental perspectives on the causes of an autism spectrum disorder in their children.
Parental perspectives on the causes of an autism spectrum disorder in their children.
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DOI：
10.1007/s10897-005-9002-7
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发表时间：
2006-02-01
影响因子：
1.9
通讯作者：
Lewis, M E S
中科院分区：
文献类型：
--
作者：
Mercer, L;Creighton, S;Lewis, M E S
自闭症谱系障碍 (ASD) 是一种复杂的神经发育障碍，具有多种生物学原因，包括遗传、综合征和环境。这种病因的异质性极大地影响了父母了解孩子诊断的需求。一项描述性调查旨在调查家长对其孩子自闭症谱系障碍原因的看法。在回答问卷的41位家长中，遗传影响（90.2%）、围产期因素（68.3%）、饮食（51.2%）、产前因素（43.9%）和疫苗（40.0%）被认为是最显着的影响因素。家长报告了不准确的高复发风险、对各种假定因素的贡献的误解、对孩子诊断的内疚感和责备感，以及缺乏非遗传学专业人士对遗传咨询的倡导。这项研究让临床医生和研究人员进一步了解父母认为哪些因素导致了孩子被诊断为自闭症谱系障碍，并将有助于促进这些家庭的遗传咨询。
Autism Spectrum Disorders (ASDs) are complex neurodevelopmental disorders with many biological causes, including genetic, syndromic and environmental. Such etiologic heterogeneity impacts considerably upon parents' needs for understanding their child's diagnosis. A descriptive survey was designed to investigate parental views on the cause(s) of ASD in their child. Among the 41 parents who replied to the questionnaire, genetic influences (90.2%), perinatal factors (68.3%), diet (51.2%), prenatal factors (43.9%) and vaccines (40.0%) were considered to be the most significant contributory factors. Parents reported inaccurately high recurrence risks, misperceptions of the contribution of various putative factors, feelings of guilt and blame regarding their child's diagnosis, as well as a lack of advocacy for genetic counseling by non-geneticist professionals. This study offers clinicians and researchers further insight into what parents believe contributed to their child's diagnosis of ASD and will help facilitate genetic counseling for these families.