Soft Tissue Sarcoma Across the Age Spectrum: A Population-Based Study From the Surveillance Epidemiology and End Results Database

Soft Tissue Sarcoma Across the Age Spectrum: A Population-Based Study From the Surveillance Epidemiology and End Results Database
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DOI:
10.1002/pbc.23252
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发表时间:
2011-12-01
影响因子:
3.2
通讯作者:
Spunt, Sheri L.
Spunt, Sheri L.
中科院分区:
医学3区
文献类型:
--
作者:
Ferrari, Andrea;Sultan, Iyad;Spunt, Sheri L.

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背景软组织肉瘤(STS)是一组异质性间叶恶性肿瘤,发生在整个生命周期。年龄对疾病特征和结局的影响尚不清楚。方法.我们分析了SEER数据库中1973年至2006年登记的所有STS病例的临床特征和结局。结果有48,012例病例符合选择标准。小于20岁的个体占5.6%,横纹肌肉瘤是最常见的亚型。在成人中,最常见的类型是卡波西肉瘤,纤维组织细胞肿瘤和平滑肌肉瘤。横纹肌肉瘤是唯一一个中位年龄
Background. Soft tissue sarcomas (STS) are a heterogeneous group of mesenchymal malignancies that occur throughout the life-span. The impact of age on disease features and outcome is unclear. Methods. We analyzed the clinical features and outcome of all STS cases registered between 1973 and 2006 in the SEER database. Results. There were 48,012 cases that met the selection criteria. Individuals less than 20 years of age represented 5.6%, with rhabdomyosarcoma being the most common subtype. In adults, the most common types were Kaposi sarcoma, fibrohistiocytic tumors, and leiomyosarcoma. Rhabdomyosarcoma was the only entity with a median age