Effects of a magnetic field and magnetization force on protein crystal growth. Why does a magnet improve the quality of some crystals?

Effects of a magnetic field and magnetization force on protein crystal growth. Why does a magnet improve the quality of some crystals?
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DOI:
10.1107/s0907444902014415
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发表时间:
2002-10-01
期刊:
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
影响因子:
--
通讯作者:
Wakayama, NI
Wakayama, NI
中科院分区:
其他
文献类型:
--
作者:
Ataka, M;Wakayama, NI

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在磁铁中生长的一些蛋白质晶体表现出比对照更好的质量的可能原因讨论如下。(1)沉降的三维核能够具有与核合并到其中的底层母晶体相同的取向。(2)蛋白质溶液可能变得更加粘稠,导致对流减少。(3)如果通过使用不均匀磁场产生向上的力,则密度差异的影响可以变得不那么显著,从而导致自然对流的减少和晶体沉降的延迟。
Probable reasons why some protein crystals grown in a magnet exhibited better quality than control are discussed as follows. (1) Sedimenting three-dimensional nuclei are able to have the same orientation as the underlying, mother crystal into which the nuclei merge. (2) Protein solution may become more viscous, leading to reduction of convection. (3) If an upward force is generated by use of an inhomogeneous magnetic field, the effects of the density differences can be made less significant, causing the reduction of natural convection and the retardation of crystal sedimentation.