Stochastic feedback and the regulation of biological rhythms
Stochastic feedback and the regulation of biological rhythms
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DOI：
10.1209/epl/i1998-00366-3
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发表时间：
1998-08-15
期刊：
影响因子：
--
通讯作者：
Stanley, HE
中科院分区：
文献类型：
--
作者：
Ivanov, PC;Amaral, LAN;Stanley, HE
我们基于“随机反馈”的概念，提出了一种解决生物节律如何自发自我调节问题的通用方法。我们通过在粗粒度层面考虑心率的神经自主调节来说明这种方法。该模型生成复杂的动力学，并成功地解释了心脏变异性的关键特征，包括 1/f 功率谱、变化分布的函数形式和标度，以及指示非线性动力学的傅立叶相位中的相关性。
We propose a general approach to the question of how biological rhythms spontaneously self-regulate, based on the concept of "stochastic feedback". We illustrate this approach by considering at a coarse-grained level the neuroautonomic regulation of the heart rate. The model generates complex dynamics and successfully accounts for key characteristics of cardiac variability, including the 1/f power spectrum, the functional form and scaling of the distribution of variations, and correlations in the Fourier phases indicating nonlinear dynamics.