Perceptual specificity in visual object priming: functional magnetic resonance imaging evidence for a laterality difference in fusiform cortex
Perceptual specificity in visual object priming: functional magnetic resonance imaging evidence for a laterality difference in fusiform cortex
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DOI：
10.1016/s0028-3932(00)00087-7
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发表时间：
2001-01-01
期刊：
影响因子：
2.6
通讯作者：
Schacter, DL
中科院分区：
文献类型：
--
作者：
Koutstaal, W;Wagner, AD;Schacter, DL
一次看到一个物体可能会促进或启动对同一物体的处理（如果稍后再次遇到该物体）。对于不同但感知上相似的对象（作为最初呈现对象的替代范例或“标记”），也可能会发现这种启动（但水平较低）。我们使用事件相关的功能磁共振成像（fMRI）程序探索了这种感知特异性的神经相关性，对比了参与者对先前呈现的物体（重复相同）、先前呈现的物体的替代样本（重复不同）或全新物体（新颖）做出物体分类决策（大小判断）时的神经活动。与新物体相比，许多额叶区域（包括双侧额叶盖、双侧后下额叶/中央前叶、左前下额叶和上额叶皮质）和多个晚期视觉和后部区域（包括中枕叶、梭形、梭形海马旁、楔前叶和后扣带回，均为双侧）与新物体相比，重复观察的神经活动减少。在其中几个区域（双侧后下额叶、右侧楔前叶、双侧中枕叶、双侧梭形、双侧海马旁和双侧顶上叶），观察到相同样本比不同样本有更大的重复引起的减少。此外，与左梭状皮层相比，右侧梭状（枕颞）皮层对不同样本和相同样本的启动显着减少。这些发现与来自分割视野研究的行为证据以及强调右枕颞叶皮层在处理特定视觉形式信息中的关键作用的神经心理学证据相一致。讨论了左梭形的表征功能作用中可能存在的差异。 (C) 2000 Elsevier Science Ltd. 保留所有权利。
Seeing an object on one occasion may facilitate or prime processing of the same object if it is later again encountered. Such priming may also be found - but at a reduced level - for different but perceptually similar objects that are alternative exemplars or 'tokens' of the initially presented object. We explored the neural correlates of this perceptual specificity using event-related functional magnetic resonance imaging (fMRI) procedures, contrasting neural activity when participants made object classification decisions (size judgments) regarding previously presented objects (repeated same), alternative exemplars of previously presented objects (repeated different), or entirely new objects (novel). Many frontal regions (including bilateral frontal operculum, bilateral posterior inferior frontal/precentral, left anterior inferior frontal, and superior frontal cortices) and multiple late visual and posterior regions (including middle occipital, fusiform, fusiform-parahippocampal, precuneus, and posterior cingulate, all bilaterally), demonstrated reduced neural activity for repeated compared to novel objects. Greater repetition-induced reductions were observed for same than for different exemplars in several of these regions (bilateral posterior inferior frontal, right precuneus, bilateral middle occipital, bilateral fusiform, bilateral parahippocampal and bilateral superior parietal). Additionally, right fusiform (occipitotemporal) cortex showed significantly less priming for different versus same exemplars than did left fusiform. These findings converge with behavioral evidence from divided visual field studies and with neuropsychological evidence underscoring the key role of right occipitotemporal cortex in processing specific visual form information; possible differences in the representational-functional role of left fusiform are discussed. (C) 2000 Elsevier Science Ltd. All rights reserved.