Non-toxic peptides from toxic cyanobacteria, Oscillatoria agardhii

Non-toxic peptides from toxic cyanobacteria, Oscillatoria agardhii
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DOI:
10.1016/s0040-4020(99)01017-0
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发表时间:
2000-01-28
期刊:
影响因子:
2.1
通讯作者:
Harada, K
Harada, K
中科院分区:
化学3区
文献类型:
--
作者:
Fujii, K;Sivonen, K;Harada, K

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为了阐明蓝藻产生的无毒和肝毒性肽之间的生物合成关系,我们比较了有毒和无毒蓝藻,颤藻(Planktothrix)agardhii的次级代谢产物。从有毒的O. agardhii菌株97和CYA128。从无毒的O.无菌菌株2和18。(C)2000爱思唯尔科技有限公司版权所有。
For the elucidation of the biosynthetic relationship between non-toxic and hepatotoxic peptides produced by cyanobacteria, we compared the secondary metabolites from the toxic and non-toxic cyanobacteria, Oscillatoria (Planktothrix) agardhii. Three groups of peptides, cyclic depsipeptides having a 3-amino-6-hydroxy-2-piperidone moiety, a cyclic nonapeptide and cyclic peptides possessing an ureido linkage were isolated together with microcystins from the toxic O. agardhii strains 97 and CYA128. A tricyclic peptide composed of 14 amino acid residues was isolated from the non-toxic O. agardhii strains 2 and 18. (C) 2000 Elsevier Science Ltd. All rights reserved.