Personality and cancer survival: the Miyagi cohort study
Personality and cancer survival: the Miyagi cohort study
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DOI：
10.1038/sj.bjc.6602610
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发表时间：
2005-06-06
影响因子：
8.8
通讯作者：
Tsuji, I
中科院分区：
文献类型：
--
作者：
Nakaya, N;Tsubono, Y;Tsuji, I
我们在日本进行的一项基于人群的前瞻性队列研究中检验了性格在癌症结果中发挥作用的假设。 1990年7月，41 442名日本居民完成了艾森克人格问卷修订版简表和各种健康习惯调查问卷，1993年1月至1997年12月期间，其中发现了890例癌症病例。对这890例病例进行随访至2001年3月，共查明全因死亡356例。 Cox 比例风险回归用于根据四个人格分量表（外向性、神经质、精神病性和谎言）的四个评分水平来估计死亡风险比 (HR)，并调整潜在的混杂因素。每个人格分量表得分最高的个体与得分最低的个体相比，全因死亡的多变量 HR 为：外向性为 1.0（95% CI = 0.8 - 1.4；趋势 P = 0.73），神经质为 1.1（0.8 - 1.6；趋势 P = 0.24），精神病为 1.2（0.9 - 1.6；趋势 P = 0.73）。 0.29), 1.0 表示谎言 ( 0.7 - 1.5；趋势 P = 0.90）。日本这项基于人群的前瞻性队列研究获得的数据并不支持人格与癌症生存相关的假设。
We tested the hypothesis that personality plays a role in cancer outcome in a population-based prospective cohort study in Japan. In July 1990, 41 442 residents of Japan completed a short form of the Eysenck Personality Questionnaire-Revised and a questionnaire on various health habits, and between January 1993 and December 1997, 890 incident cases of cancer were identified among them. These 890 cases were followed up until March 2001, and a total of 356 deaths from all causes was identified among them. Cox proportional-hazards regression was used to estimate the hazard ratio (HR) of death according to four score levels on each of four personality subscales ( extraversion, neuroticism, psychoticism, and lie), with adjustment for potential confounding factors. Multivariable HRs of deaths from all causes for individuals in the highest score level on each personality subscale compared with those at the lowest level were 1.0 for extraversion ( 95% CI = 0.8 - 1.4; Trend P = 0.73), 1.1 for neuroticism ( 0.8 - 1.6; Trend P = 0.24), 1.2 for psychoticism ( 0.9 - 1.6; Trend P = 0.29), and 1.0 for lie ( 0.7 - 1.5; Trend P = 0.90). The data obtained in this population-based prospective cohort study in Japan do not support the hypothesis that personality is associated with cancer survival.