Retention and remineralization effect of moisture tolerant resin-based sealant and glass ionomer sealant on non-cavitated pit and fissure caries: Randomized controlled clinical trial
Retention and remineralization effect of moisture tolerant resin-based sealant and glass ionomer sealant on non-cavitated pit and fissure caries: Randomized controlled clinical trial
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DOI：
10.1016/j.jdent.2019.05.027
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发表时间：
2019-07-01
影响因子：
4.4
通讯作者：
Comisi, John C.
中科院分区：
文献类型：
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作者：
Alsabek, Laith;Al-Nerabieah, Zuhair;Comisi, John C.
导言/目标：窝沟封闭剂是预防牙科的重要组成部分，应通过作为一个重要组成部分的微创牙科由于其深刻的利益，我们的patients.Methods：本研究设计是一个单盲，分口，随机对照临床试验。选择了40名6-9岁的患者。选择根据国际龋齿检测和评估系统II（ICDAS II）评分为1或2的第一恒磨牙的咬合面，以及使用DIAGNOdent装置（Kayo（R），比伯拉赫，德国）评分在14-30之间的第一恒磨牙的咬合面，并记录读数。随机选择口腔的一侧放置耐湿性树脂密封剂或玻璃离聚物密封剂，然后将第二种材料放置在另一侧。在3个月和6个月时分析这些材料的保留。结果：3个月后，A组（Embrace（TM）WetBone（TM））中有38/40（95%）的牙齿完全固位，B组（Fuji TRIAGE（R））中有35/40（87.5%）的牙齿完全固位。此外，A组中没有密封剂完全丢失，而B组中有3种密封剂完全丢失（7.5%）。在此期间，两组的封合剂保留差异无统计学意义（P > 0.05），在6个月时，A组34/40（85%）和B组25/40（62.5%）的封合剂完全保留。此外，A组的部分丢失为2/40（5%），而B组为7/40（17.5%）。A组和B组的总丢失率分别为4/40（10%）和8/40（20%）。随访6个月后，两组的封闭剂保留率差异有统计学意义（P < 0.05），A组和B组的DIAGNOdent读数的初始平均值分别为22.42和22.8。6个月后，两组的DIAGNOdent平均值均有所下降，这种差异具有统计学意义。然而，当将A组与B组在再矿化效应方面进行比较时，发现差异无统计学显著性（p > 0.05）。在本研究的范围内，我们肯定了咬合面龋损，这是限制釉质和需要手术干预，可以通过用亲水性树脂密封剂和玻璃离聚物密封剂材料密封病变而在临床上阻止。在六个月的随访后，Embrace（TM）WetBone（TM）在固位测试中显示出优于玻璃离子密封剂的优势。
Introduction/objectives: Pit and fissure sealants are an essential part of preventive dentistry and should be adopted as a crucial part of the minimally invasive dentistry due to their profound benefit to our patients.Methods: The study design is a single-blind, split-mouth, randomized controlled clinical trial. Forty patients between age 6-9 were selected. First permanent molars' occlusal surfaces with scores of 1, or 2 according to the International Caries Detection and Assessment System II (ICDAS II) and with scores between 14-30 by using DIAGNOdent device (Kayo (R), Biberach, Germany) were selected and readings recorded. One side of the mouth was randomly chosen to have either the moisture tolerant resin sealant or the glass ionomer sealant placed, and then the second material was placed on the other side. The retention of these materials was analyzed at 3 and 6 months. The sealants were then removed and DIAGNOdent readings were subsequently taken.Results: After three months, full retention was found in 38/40 (95%) teeth in Group A (Embrace (TM) WetBone (TM)) and 35/40 (87.5%) teeth in Group B (Fuji TRIAGE (R)). Additionally, no sealant suffered a total loss in group A, whereas, three sealants were totally lost (7.5%) in group B. The difference in sealant retention in two groups in this period was not found to be statistically significant (P > 0.05).At six months, full retention was found in Group A 34/40 (85%) and 25/40 (62.5%) in Group B. Also, the partial loss in Group A was 2/40 (5%) whereas in Group B 7/40 (17.5%). Also, the total loss was 4/40 (10%) and 8/40 (20%) in Group A and B, respectively. The difference in sealant retention in two groups after six months follow-up was found statistically significant (P < 0.05).The initial mean values of DIAGNOdent readings were 22.42 and 22.8 in Group A and Group B, respectively. After six months, DIAGNOdent mean values revealed a drop in both groups, and this difference was statistically significant. Nevertheless, when Group A was compared to Group B in terms of remineralization effect, the differences were found not to be statistically significant (p > 0.05).Conclusions: Within the limitation of this study, we affirmed that occlusal caries lesions, which is restrictive to enamel and in need of surgical intervention, can be arrested clinically by sealing the lesion with both a hydrophilic resin sealant and glass ionomer sealant materials. Embrace (TM) WetBone (TM) showed superiority over the glass ionomer sealant tested in retention after six months follow up.