Alcohol consumption and subclinical findings on magnetic resonance imaging of the brain in older adults - The Cardiovascular Health Study
Alcohol consumption and subclinical findings on magnetic resonance imaging of the brain in older adults - The Cardiovascular Health Study
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DOI：
10.1161/hs0901.095723
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发表时间：
2001-09-01
期刊：
影响因子：
8.3
通讯作者：
Siscovick, DS
中科院分区：
文献类型：
--
作者：
Mukamal, KJ;Longstreth, WT;Siscovick, DS
背景和目的：脑MRI的亚临床表现与老年人认知和神经功能较差有关。我们试图确定如何饮酒是与这些findings.Methods的心血管健康研究的一部分，3660名65岁及以上的成年人进行了MRI的大脑从1992年至1994年。我们排除了284名有明确脑血管病史的参与者。我们评估了在最接近MRI日期的年度诊所访视中自我报告的啤酒、葡萄酒和白酒的摄入量，并将参与者分为6类：戒酒者、前饮酒者、
Background and Purpose-Subclinical findings on MRI of the brain are associated with poorer cognitive and neurological function among older adults. We sought to determine how alcohol consumption is related to these findings.Methods-As part of the Cardiovascular Health Study, 3660 adults aged 65 years and older underwent MRI of the brain from 1992 to 1994. We excluded 284 participants with a confirmed history of cerebrovascular disease. We assessed self-reported intake of beer, wine, and liquor at the annual clinic visit closest to the date of the MRI and grouped participants into 6 categories: abstainers, former drinkers,