THYROID-DISEASE AND BREAST-CANCER
THYROID-DISEASE AND BREAST-CANCER
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DOI：
10.1007/bf03348865
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发表时间：
1993-05-01
影响因子：
5.4
通讯作者：
SMYTH, PPA
中科院分区：
文献类型：
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作者：
SMYTH, PPA
由于乳腺癌与甲状腺功能减退、甲状腺功能亢进和非毒性甲状腺肿有关，对甲状腺疾病与乳腺癌之间关系的文献回顾并没有提供确凿的证据来建立因果关系。大多数关于甲状腺肿大和乳腺癌之间关系的报告来自地方性缺碘地区，这些报告依赖于颈部触诊。本研究的贡献在于应用高灵敏度的超声诊断技术来研究乳腺癌患者甲状腺体积和解剖结构的细微变化。184例乳腺癌患者的平均甲状腺体积为20.4+/-1.0 ml，显著高于年龄匹配对照组的12.9+/-1.2 ml (p
A review of the literature on the relationship between thyroid disorders and breast cancer does not provide conclusive evidence for the establishment of a causal relationship as breast cancer has been associated with hypothyroidism, hyperthyroidism and nontoxic goiter. Most reports on the association of thyroid enlargement and breast cancer have emanated from areas of endemic iodine deficiency and these reports have relied on neck palpation. The contribution of the present study is in the application of the highly sensitive technique of diagnostic ultrasound to the investigation of subtle changes in thyroid volume and anatomy in patients with breast cancer. The mean thyroid volume of 20.4+/-1.0 ml in 184 breast cancer patients was significantly greater than that of 12.9+/-1.2 ml in age-matched controls (p