Nickel-Catalyzed Decarbonylative Addition of Anhydrides to Alkynes
Nickel-Catalyzed Decarbonylative Addition of Anhydrides to Alkynes
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DOI：
10.1021/ja806569h
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发表时间：
2008-12-24
影响因子：
15
通讯作者：
Matsubara, Seijiro
中科院分区：
文献类型：
--
作者：
Kajita, Yuichi;Kurahashi, Takuya;Matsubara, Seijiro
在分子间镍催化的加成反应中，邻苯二甲酸酐与炔烃反应得到取代的异香豆素。提出了催化循环的关键步骤是助剂促进还原消除Ni(0)的机理。
An intermolecular nickel-catalyzed addition reaction has been developed where phthalic anhydrides react with alkynes to afford substituted isocoumarins. A mechanistic rationale is proposed, implying reductive elimination of Ni(0) promoted by ZnCl2 cocatalyst as the key step of the catalytic cycle.