Validación de un test de tamizaje para el diagnóstico de demencia asociada a edad, en Chile

Validación de un test de tamizaje para el diagnóstico de demencia asociada a edad, en Chile
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智利痴呆症协会诊断测试的验证

DOI:
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发表时间:
2004
期刊:
影响因子:
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通讯作者:
Gonzalo Klaasen P
Gonzalo Klaasen P
中科院分区:
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文献类型:
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作者:
Pilar Quiroga L;Cecilia Albala B;Gonzalo Klaasen P

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:在100名65岁以上的受试者样本中验证诊断测试(85名来自“年龄相关痴呆”项目,15名确诊为痴呆)。所有人都接受了由训练有素的神经学家进行的完整的神经心理测试,这构成了诊断痴呆症的“金标准”。一位独立的采访者将MMSE应用于受试者,并将PFAQ应用于近亲举报人。采用ROC曲线计算截断点。考虑到受教育程度低和受教育程度高的人群结果的差异,选择敏感性和特异性平衡较好的点。
: Validation of the diagnostic test in a sample of 100subjects over 65 years old (85 from the project «Age associated dementias» and 15 with a con-firmed diagnosis of dementia). All were subjected to a complete neuropsychological test by atrained neurologist, that constituted the «gold standard» for the diagnosis of dementia. An inde-pendent interviewer applied the MMSE to the subjects and the PFAQ to a next of kin informer.Cutoff points were calculated using ROC curves. The points with the better equilibrium betweensensitivity and specificity were selected, considering differences in results between groups withlow and high educational level.