Gait speed predicts decline in attention and psychomotor speed in older adults: The health aging and body composition study
Gait speed predicts decline in attention and psychomotor speed in older adults: The health aging and body composition study
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DOI：
10.1159/000111577
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发表时间：
2007-01-01
影响因子：
5.7
通讯作者：
Rosano, Caterina
中科院分区：
文献类型：
--
作者：
Inzitari, Marco;Newman, Anne B.;Rosano, Caterina
背景/目标：步态速度与老年社区居民的注意力和精神运动速度存在横断面相关。目前尚不清楚步态速度是否预示着这些认知领域会随着时间的推移而下降。方法：对 2,776 名健康、衰老和身体成分研究参与者（平均年龄 +/- SD 73.5 +/- 2.8 岁，53% 女性，37% 黑人）进行基线测量，超过 6 m 的通常步态速度 (m/s)。在基线和 5 年后进行数字符号替换测试 (DSST)，以评估注意力和精神运动速度。我们使用多变量逻辑回归模型来计算步态速度四分位数的 DSST 5 年下降风险 [>1 SD 平均变化 (9 点)]，并根据人口统计、体重、体力活动、合并症、抑郁症和改良简易精神状态检查进行调整。结果：5 年后，389 名（17.1%）参与者的 DSST 下降。与步态速度最高四分位数 (> 1.35 m/s) 的参与者相比，步态速度最低四分位数 (> 1.35 m/s) 的参与者 (
Background/Aims: Gait speed is cross-sectionally associated with attention and psychomotor speed in older community dwellers. It is unclear if gait speed predicts decline in these cognitive domains over time. Methods: Usual gait speed (m/s) over 6 m was measured at baseline in 2,776 Health, Aging and Body Composition Study participants (mean age +/- SD 73.5 +/- 2.8 years, 53% women, 37% blacks). The Digit Symbol Substitution Test (DSST) was administered at baseline and after 5 years to assess attention and psychomotor speed. We used multivariate logistic regression models to calculate the risk of DSST 5-year decline [>1 SD from mean change (9 points)] across quartiles of gait speed, adjusting for demographics, weight, physical activity, comorbidities, depression and Modified Mini-Mental State Examination. Results: After 5 years, 389 (17.1%) participants declined in DSST. Compared to those in the highest quartile of gait speed (> 1.35 m/s), participants in the lowest quartile (