Restriction enzyme analysis of partially transformation-defective mutants of acute leukemia virus MC29
Restriction enzyme analysis of partially transformation-defective mutants of acute leukemia virus MC29
复制标题
急性白血病病毒MC29部分转化缺陷突变体的限制性内切酶分析
DOI:
10.1128/jvi.44.2.711-715.1982
复制
发表时间:
1982
影响因子:
5.4
通讯作者:
M. Hayman
中科院分区:
文献类型:
--
作者:
P. Enrietto;M. Hayman
Restriction enzyme mapping and limited sequence analysis have been used to study the generation and genome structure of three partial-transformation mutants of avian acute leukemia virus MC29. The three mutants, td10A, td10C, and td10H, could be shown to have sustained overlapping deletions of 200, 400, and 600 base pairs, respectively, in their genomes. The precise location of the deletions was mapped within the v-myc gene of the mutants by limited sequence analysis of cloned MC29 DNA. The data obtained are discussed in terms of the effect of these deletions on the mechanism of transformation by MC29.
DOI:
10.1101/sqb.1980.044.01.086
发表时间:
1980
期刊:
Cold Spring Harbor symposia on quantitative biology
影响因子:
--
作者:
Bister,K;Duesberg,PH
通讯作者:
Duesberg,PH