Restriction enzyme analysis of partially transformation-defective mutants of acute leukemia virus MC29

Restriction enzyme analysis of partially transformation-defective mutants of acute leukemia virus MC29
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急性白血病病毒MC29部分转化缺陷突变体的限制性内切酶分析

DOI:
10.1128/jvi.44.2.711-715.1982
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发表时间:
1982
影响因子:
5.4
通讯作者:
M. Hayman
M. Hayman
中科院分区:
医学2区
文献类型:
--
作者:
P. Enrietto;M. Hayman

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Restriction enzyme mapping and limited sequence analysis have been used to study the generation and genome structure of three partial-transformation mutants of avian acute leukemia virus MC29. The three mutants, td10A, td10C, and td10H, could be shown to have sustained overlapping deletions of 200, 400, and 600 base pairs, respectively, in their genomes. The precise location of the deletions was mapped within the v-myc gene of the mutants by limited sequence analysis of cloned MC29 DNA. The data obtained are discussed in terms of the effect of these deletions on the mechanism of transformation by MC29.
禽急性白血病病毒的遗传结构。
DOI: 10.1101/sqb.1980.044.01.086
发表时间: 1980
期刊: Cold Spring Harbor symposia on quantitative biology
影响因子: --
作者:
Bister,K;Duesberg,PH
通讯作者: Duesberg,PH