Brain Responses to Food Logos in Obese and Healthy Weight Children
Brain Responses to Food Logos in Obese and Healthy Weight Children
复制标题
DOI：
10.1016/j.jpeds.2012.10.003
复制
发表时间：
2013-04-01
影响因子：
5.1
通讯作者：
Savage, Cary R.
中科院分区：
文献类型：
--
作者：
Bruce, Amanda S.;Lepping, Rebecca J.;Savage, Cary R.
目的评估健康体重和肥胖儿童对常见食物和非食物标识的大脑激活情况。研究设计10名健康体重儿童（平均体重指数在第50百分位数）和10名肥胖儿童（平均体重指数在第97.9百分位数）完成自我控制的自我报告措施。结果与健康体重儿童相比，肥胖儿童双侧中/下前额叶皮层对食物标识的脑激活显著减少，该区域参与认知控制。结论肥胖儿童在观看食物标识时，与健康体重儿童相比，认知控制相关区域的脑激活显著减少。这提供了初步的神经影像学证据，表明肥胖儿童可能更容易受到食品广告的影响。（J Pediatr 2013;162：759-64）。
Objective To evaluate brain activation in response to common food and nonfood logos in healthy weight and obese children.Study design Ten healthy weight children (mean body mass index in the 50th percentile) and 10 obese children (mean body mass index in the 97.9th percentile) completed self-report measures of self-control. They then underwent functional magnetic resonance imaging while viewing food and nonfood logos.Results Compared with the healthy weight children, obese children showed significantly less brain activation to food logos in the bilateral middle/inferior prefrontal cortex, an area involved in cognitive control.Conclusion When shown food logos, obese children showed significantly less brain activation than the healthy weight children in regions associated with cognitive control. This provides initial neuroimaging evidence that obese children may be more vulnerable to the effects of food advertising. (J Pediatr 2013;162:759-64).